Research Group

  • Prof. James McCluskey, Principal Investigator
  • Dr Mandvi Bharadwaj, Co-Investigator
  • Prof Jamie Rossjohn, Co-Investigator


  • University of Melbourne, Parkville, Australia


  • To Monitor the Mechanism and Tissue-specificity of Cross-reactive, Allogeneic T Cells

This project will explore the basis of unexpected immune reactions whereby the immune system mistakes one molecular structure for another, a phenomenon known as cross-reactivity. The project will examine how often this is due to molecular mimicry, potentially explaining why immune T cells sometimes react inappropriately and cause harmful effects for the host. This information will help us to alleviate much of the morbidity and mortality associated with organ transplantation.

Progress Report
Final Report