Grant Awards in April & October 2006

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Principal Investigator Project Title/Link
1. Grant Awards in Cycle XV & XVI  
1.1 Conventional ROTRF Research Grants - Cycle XV  
Dr Simi Ali
University of Newcastle, Newcastle-upon-Tyne, UK
Non-Glycosaminoglycan-Binding Chemokine Receptor Agonists: A Novel Route to Anti-Rejection Therapy?
Dr Michael Autieri
Temple University School of Medicine, Philadelphia, USA
The Role of Allograft-Inflammatory Factor-1 in Development of Graft Vascular Disease
Dr Anita S. Chong
The University of Chicago, Chicago, USA
Bacterial Infections and Transplantation Tolerance
Dr Daniel Goldstein
Yale University School of Medicine, New Haven, USA
Role of Innate B1 Lymphocytes in Neonatal Transplant Tolerance
Dr Gregg A. Hadley
The Ohio State University, Columbus, USA
Mechanisms Underlying Immune Destruction of Pancreatic Islet Transplants
Dr Irma Joosten
Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Effect of Regulatory T Cell Diversity on the Immune Response
Dr Karl Lemström
University of Helsinki, Helsinki, Finland
Role of Hypoxia Inducible Factor-1 in Cardiac Allograft Vasculopathy
Dr Benjamin Medoff
Massachusetts General Hospital, Boston, USA
The Role of the White Blood Cell Attractant CXCL10 in the Development of Lung Injury Following Lung Transplantation
Dr Hao Wang
University of Western Ontario, London, Canada
Induction of Transplant Tolerance in Sensitized Recipients
Dr Li Zhang
University of Maryland, Baltimore, USA
Integrin Mac-1 on Antigen-Presenting Cells Is Key to the Development of Peripheral Immune Tolerance
1.2 Conventional ROTRF Research Grants - Cycle XVI  
Dr Maria-Luisa Alegre
The University of Chicago, Chicago, USA
Treg Specificity in a Mouse Cardiac Transplantation Tolerance Model
Dr Masato Imai
Beth Israel Deaconess Medical Center, Boston, USA
NTPDase-1/CD39 Ameliorates Transplant Arteriosclerosis
Prof. James McCluskey
The University of Melbourne, Parkville, Australia
Understanding Why Organ Transplants Are Rejected by the Host Immune System
Dr Wei-Ping Min
University of Western Ontario, London, Canada
Protection of Donor Organs in Transplantation
Prof. Yorgo Modis
Yale University, New Haven, USA
The Structural Basis of Innate Immune Sensing and Signaling by Toll-Like Receptors
Dr Julian Pratt
Leeds University, Leeds, UK
Ischaemic Epigenetics in the Transplanted Kidney
1.3 Clinical ROTRF Research Grants - Cycle XV  
Dr Anthony Dorling
Imperial College London, London, UK
Understanding How Antibodies and B Cells Contribute to the ‘Chronic’ Rejection of Transplanted Kidneys
Prof. Rudolphina J.M. ten Berge
Academical Medical Center, Amsterdam, The Netherlands
Immunological Injury and Mechanisms of Self Defense in Subclinical Renal Allograft Rejection
1.4 Clinical ROTRF Research Grants - Cycle XVI  
Dr Henrik Petrowsky
University Hospital Zurich, Zürich, Switzerland
Protective Mechanisms of Pentoxyfilline for Liver Surgery and Liver Transplantation
Dr Andrea Zachary
Johns Hopkins University, Baltimore, USA
Detecting Humoral Sensitization
2. ROTRF/JDRF Joint Initiative Grant Awards  
2.1 ROTRF/JDRF Joint Grant Awards - Cycle XVI  
Dr Ariela Benigni
Mario Negri Institute for Pharmacological Research, Bergamo, Italy
Generation of New Blood Vessels and Immunomodulation without Drugs to Improve Survival of Islet Grafts
Dr David M. Rothstein
Yale University, New Haven, USA
How Experimental Agents Prevent Islet Transplant Rejection by Inducing Different Types of Regulatory T Cells
Dr Charmaine Simeonovic
The Australian National University, Canberra, Australia
Immune Destruction and Protection of Pancreatic Islet Transplants